| 产品详情 |
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| Antigenic Specificity | HOXA11 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HOXA11 Polyclonal Antibody. HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35;q24) or t(10:14)(q24;qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates |
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| Immunogen | n/a |
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| Other Names | HOX11 |
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| Gene, Accession # | Entrez: 103692131, 15396, 3207; Uniprot: P31270, P31311 |
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| Catalog # | PA1-41396 |
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| Price | |
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| Order / More Info | HOXA11 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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