产品详情 |
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Antigenic Specificity | HOXA13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:1000-1:4000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HOXA13 Polyclonal Antibody. HoxA13 and HoxD13 also bind to other BMP and TGF-beta/Activin-regulated Smad proteins including Smad1 and Smad2, but not Smad4. In humans and mice, loss of HOXA13 function causes defects in the growth and patterning of the digits and interdigital tissues. Analysis of HoxA13 expression reveals a pattern of localization overlapping with sites of reduced Bmp2 and Bmp7 expression in HoxA13 mutant limbs. HoxA13 regulates Bmp2 and Bmp7 expression, providing a link between HoxA13, its target genes and the specific developmental processes affected by loss of HoxA13 function. |
Immunogen | n/a |
Other Names | Homeobox protein Hox-A13; Homeobox protein Hox-1J; HOXA13; HOX1J |
Gene, Accession # | Entrez: 15398, 500129; Uniprot: Q62424 |
Catalog # | PA5-76440 |
Price | |
Order / More Info | HOXA13 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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