| 产品详情 |
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| Antigenic Specificity | TWIST1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, equine, human, mouse, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TWIST1 Polyclonal Antibody. TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly. |
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| Immunogen | n/a |
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| Other Names | Twist homolog 1 (Drosophila), SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38 |
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| Gene, Accession # | Entrez: 100272214, 22160, 7291, 782170, 85489; Uniprot: P26687, Q15672 |
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| Catalog # | PA5-68957 |
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| Price | |
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| Order / More Info | TWIST1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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