| 产品详情 |
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| Antigenic Specificity | KDEL |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | hamster, human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor 647 conjugate |
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| Size | 50 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KDEL Polyclonal Antibody, Alexa Fluor 647. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor. |
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| Immunogen | n/a |
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| Other Names | ECGP, AU019543, AL022860, baffled, mBiP, GRP94, gp96, Targ2, GRP78, GP96, D2Wsu141e, TA-3, D2Wsu17e, SEZ-7, MIF2, endoplasmin, Tra1, Hsce70, ERp99, BIP, Grp94, Grp78, Tra-1, Sez7, TRA1, Bip |
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| Gene, Accession # | Entrez: 100773331, 14828, 22027, 25617, 3309, 362862, 7184; Uniprot: P06761, P08113, P08712, P11021, P14625, P20029, Q66HD0 |
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| Catalog # | PA1-013-A647 |
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| Price | |
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| Order / More Info | KDEL Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18644783, 19088077, 26601955 |
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