| 产品详情 |
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| Antigenic Specificity | MiTF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, ovine, rabbit, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 0.2-1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MiTF Polyclonal Antibody. Transcription factor for tyrosinase and tyrosinase-related protein 1. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigmant epithelium. This protein is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary synd |
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| Immunogen | n/a |
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| Other Names | Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32 |
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| Gene, Accession # | Entrez: 100033918, 100344730, 100732590, 101115163, 17342, 25094, 407219, 415126, 4286; Uniprot: O75030, O88368, Q08874 |
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| Catalog # | PA5-68948 |
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| Price | |
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| Order / More Info | MiTF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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