| 产品详情 |
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| Antigenic Specificity | NSMCE4A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NSMCE4A Polyclonal Antibody. NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus. |
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| Immunogen | n/a |
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| Other Names | C10orf86, NSE4A, non-structural maintenance of chromosomes element 4 homolog A |
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| Gene, Accession # | Entrez: 54780; Uniprot: Q9NXX6 |
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| Catalog # | PA5-57954 |
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| Price | |
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| Order / More Info | NSMCE4A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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