| 产品详情 |
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| Antigenic Specificity | NSUN2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NSUN2 Polyclonal Antibody. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5). |
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| Immunogen | n/a |
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| Other Names | MISU, SAKI, TRM4, 5-methycytoisine methyltransferase, Myc-induced SUN-domain-containing protein, NOL1/NOP2/Sun domain family 2, NOL1/NOP2/Sun domain family member 2, NOL1/NOP2/Sun domain family, member 2, hTrm4, substrate of AIM1/Aurora kinase B, tRNA (cytosine(34)-C(5))-methyltr |
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| Gene, Accession # | Entrez: 54888; Uniprot: Q08J23 |
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| Catalog # | PA5-58155 |
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| Price | |
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| Order / More Info | NSUN2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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