| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | EDG6 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 3.0-5 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | EDG6 Polyclonal Antibody. Edg6 is a recently cloned member of the endothelial differentiation gene (EDG) G protein-coupled receptor family. It is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P), which are structurally related lysophospholipid mediators. Binding of SPP to Edg6 activates Erk, leading to the activation of the transcription factor Elk1 and thus the mitogen-activated protein kinase (MAPK) signal transduction pathway. The protein also acts as a receptor for a lipid-derived ligand. Edg6 plays an essential role in lymphocyte cell signaling. The protein is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Human Edg6 gene is intronless and is mapped to chromosome 19p13.3 |
|---|
| Immunogen | n/a |
|---|
| Other Names | EDG6, LPC1, S1P4, SLP4, S1P receptor 4, S1P receptor Edg-6, endothelial differentiation G-protein coupled receptor 6, endothelial differentiation, G protein coupled receptor 6, endothelial differentiation, G-protein-coupled receptor 6, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6, sphingosine 1-phosphate receptor 4, sphingosine 1-phosphate receptor Edg-6 |
|---|
| Gene, Accession # | Entrez: 13611, 8698; Uniprot: O95977, Q9Z0L1 |
|---|
| Catalog # | PA5-23221 |
|---|
| Price | |
|---|
| Order / More Info | EDG6 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|