| 产品详情 |
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| Antigenic Specificity | EDG8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EDG8 Polyclonal Antibody. Sphingosine 1-phosphate receptor Edg8 is a multi-pass membrane protein belonging to the G-protein coupled receptor 1 family and coupled to both the G (i/0) alpha and G (12) subclass of heteromeric G-proteins. Edg8 acts as a receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) as well as for lysolipid mediator lysophosphatidic acid (LPA) and gives diverse physiological effect on most types of cells and tissues. Edg8 may also play a regulatory role in the transformation of radial glial cells into astrocytes and affect proliferative activity of these cells. It is widely expressed in white matter tracts of brain, spleen, peripheral blood leukocytes, placenta, lung, aorta, and fetal spleen. Over exp |
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| Immunogen | n/a |
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| Other Names | EDG8, Edg-8, S1P5, SPPR-1, SPPR-2, S1P receptor 5, S1P receptor Edg-8, endothelial differentiation G-protein-coupled receptor 8, endothelial differentiation, sphingolipid G-protein-coupled receptor, 8, sphingosine 1-phosphate receptor 5, sphingosine 1-phosphate receptor EDG8, sphingosine 1-phosphate receptor Edg-8 |
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| Gene, Accession # | Entrez: 53637, 60399, 610828, 94226; Uniprot: Q91X56, Q9H228, Q9JKM5 |
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| Catalog # | PA5-23195 |
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| Price | |
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| Order / More Info | EDG8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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