产品详情 |
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Antigenic Specificity | KIM-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KIM-1 Polyclonal Antibody. HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epi |
Immunogen | n/a |
Other Names | Hepatitis A virus cellular receptor 1, HAVcr-1, Kidney injury molecule 1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T-cell immunoglobulin mucin receptor 1, TIM, TIM-1, T-cell membrane protein 1, HAVCR1, KIM1, TIM1, TIMD1 |
Gene, Accession # | Entrez: 26762; Uniprot: Q96D42 |
Catalog # | PA5-79345 |
Price | |
Order / More Info | KIM-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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