| 产品详情 |
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| Antigenic Specificity | Coronin 1A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, chicken, equine, human, mouse, porcine, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:500-1:1000, Immunofluorescence: 1:500 - 1:1000, Immunohistochemistry: 1:5000, Western Blot: 1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Coronin 1A Polyclonal Antibody. Highly conserved coronin family of proteins/actin regulators from WD-repeat superfamily were originally identified in Dictyostelium, wherein, coronin deletions were observed to affect actin-dependent processes, such as phagocytosis, cell motility, and cytokinesis. Coronin-1A (Coro1A) belongs to Type I coronins, almost exclusively expressed in hematopoietic lineages, and plays a key role during T lymphocyte activation, migration, survival, and calcium signaling. Moreover, Coronin-1A has been documented to be dispensable for actin-dependent functions in macrophages. Coro1a-deficient mice have reduced peripheral T cells due to both an impaired survival of naive cells and migrational defects. Both CD4+ and CD8+ T |
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| Immunogen | n/a |
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| Other Names | CLABP, CLIPINA, FLJ41407, HCORO1, MGC117380, TACO, p57 |
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| Gene, Accession # | Entrez: 100064170, 100621483, 11151, 12721, 155151, 282196; Uniprot: O89053, P31146, Q91ZN1, Q92176 |
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| Catalog # | PA1-10022 |
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| Price | |
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| Order / More Info | Coronin 1A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 20217863 |
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