| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Phospho-IkB beta (Thr19, Ser23) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | canine, human, nonhuman primate |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Phospho-IkB beta (Thr19, Ser23) Polyclonal Antibody. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). |
|---|
| Immunogen | n/a |
|---|
| Other Names | I-kappa-B-beta; NF-kappa-B inhibitor beta; NF-kappa-BIB; TR-interacting protein 9; TRIP-9; ikB-B; ikB-beta; ikappaBbeta; thyroid receptor-interacting protein 9 |
|---|
| Gene, Accession # | Entrez: 4793, 484519; Uniprot: Q15653 |
|---|
| Catalog # | PA5-17517 |
|---|
| Price | |
|---|
| Order / More Info | Phospho-IkB beta (Thr19, Ser23) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|