| 产品详情 |
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| Antigenic Specificity | Phospho-IKK gamma (Ser376) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IKK gamma (Ser376) Polyclonal Antibody. Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B- mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Invo |
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| Immunogen | n/a |
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| Other Names | FIP-3, FIP3, I-kappa-B kinase gamma, IKBKG, IKK-gamma, IKKAP1, IKKG, IkB kinase gamma subunit, IkB kinase-associated protein 1, Inhibitor of nuclear factor kappa-B kinase gamma subunit, NEMO, NF-kappaB essential modifier, NF-kappaB essential modulator, mF |
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| Gene, Accession # | Entrez: 8517; Uniprot: Q9Y6K9 |
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| Catalog # | PA5-37766 |
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| Price | |
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| Order / More Info | Phospho-IKK gamma (Ser376) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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