产品详情 |
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Antigenic Specificity | GAPDH Loading Control |
Clone | GA1R |
Host Species | Mouse |
Reactive Species | bacteria, chicken, hamster, human, insect, mouse, rabbit, rat, yeast |
Isotype | IgG1 |
Format | DyLight 488 conjugate |
Size | 50 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GAPDH Loading Control Monoclonal Antibody (GA1R), DyLight 488. GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 100009074, 100736557, 14433, 24383, 2597, 374193; Uniprot: P00356, P04406, P04797, P16858, P46406 |
Catalog # | MA5-15738-D488 |
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Order / More Info | GAPDH Loading Control Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 25897129, 26219498, 27334581, 29472585 |
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