产品详情 |
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Antigenic Specificity | CD50 (ICAM-3) |
Clone | CBR-IC3/1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD50 (ICAM-3) Monoclonal Antibody (CBR-IC3/1), eBioscience™. CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; |
Immunogen | n/a |
Other Names | CD50, CDW50, ICAM-R, ICAM-3, intercellular adhesion molecule-3 |
Gene, Accession # | Entrez: 3385; Uniprot: P32942 |
Catalog # | BMS111 |
Price | |
Order / More Info | CD50 (ICAM-3) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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