| 产品详情 |
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| Antigenic Specificity | TACC3 |
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| Clone | OTI1E11 |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TACC3 Monoclonal Antibody (OTI1E11). TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to intera |
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| Immunogen | n/a |
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| Other Names | Transforming acidic coiled-coil-containing protein 3, ERIC-1, TACC3, ERIC1 |
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| Gene, Accession # | Entrez: 10460, 360962; Uniprot: Q9Y6A5 |
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| Catalog # | MA5-25128 |
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| Price | |
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| Order / More Info | TACC3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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