产品详情 |
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Antigenic Specificity | HOXB7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunofluorescence: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HOXB7 Polyclonal Antibody. The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups (clusters), dispersed over 4 chromosomes (HOXA, HOXB, HOXC and HOXD). HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines. HOXB7 binds to and transactivates bFGF in melanoma cell lines but SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes. HOXB7 may be a key activator of tumor-associated neoangiogenesis. |
Immunogen | n/a |
Other Names | Homeobox protein Hox-B7, Homeobox protein HHO.C1, Homeobox protein Hox-2C, HOXB7, HOX2C |
Gene, Accession # | Entrez: 3217; Uniprot: P09629 |
Catalog # | 40-2000 |
Price | |
Order / More Info | HOXB7 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 21183939, 26135503, 26968988 |
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