| 产品详情 |
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| Product Name | Piperine |
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| Description | Purity >98%. Piperine is a natural alkaloid that can be isolated from black pepper. It activates transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 µM) and modulates GABAA receptors (EC50 s = 43-60 µM). At similar levels, piperine inhibits both monoamine oxidases (MAOs), with IC50 values of 21 and 7 µM for MAO-A and MAO-B, respectively. Like other natural compounds containing methylenedioxyphenyl substituents, piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 µM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one, Bioperine, N-Piperoylpiperidin, NSC 21727 |
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| Gene, Accession, CAS # | CAS: 94-62-2 |
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| Catalog # | LS-H9429 |
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| Price | |
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| Order / More Info | Piperine from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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