产品详情 |
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Antigenic Specificity | S100A9 / MRP14, aa2-114 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Xenopus, chicken, zebrafish, mouse, rat, hamster, human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | n/a |
Concentration | n/a |
Applications | ELISA (0.1 - 0.5 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), WB (0.1 - 0.5 µg/ml) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | S100A9 / MRP14 Antibody (aa2-114) LS-C407888. Specificity: Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers. |
Immunogen | E. coli-derived human S100A9 recombinant protein (Position: T2-P114). Human S100A9 shares 59.8% and 64.5% amino acid (aa) sequence identity with mouse and rat S100A9, respectively. |
Other Names | S100A9, 60B8AG, Calgranulin B, CFAG, CAGB, Calgranulin-B, Calprotectin L1H subunit, CGLB, L1Ag, MRP14, NIF, p14, Protein S100-A9, LIAG, MAC387, MRP-14 |
Gene, Accession # | S100A9, Gene ID: 6280 |
Catalog # | LS-C407888 |
Price | |
Order / More Info | S100A9 / MRP14, aa2-114 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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