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| Product Name | Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein |
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| Description | Recombinant Human Ubiquitin-Conjugating Enzyme E2 C/UBE2C is produced with our E. coli expression system. The target protein is expressed with (Met1-Pro179) of Human UBE2C fused with a 6His tag at the N-terminus. Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 AA enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin). |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LOC458287|UBCH10|dJ447F3.2|1110015A16Rik|D2Ertd695e|im:7137135|zgc:123190 |
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| Gene, Accession, CAS # | Gene ID: 11065 |
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| Catalog # | ABIN1692235 |
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| Order / More Info | Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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