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| Product Name | AMPK activator |
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| Description | Purity >95%. AMPK activator is an indirect activator of AMP-activated protein kinase, AMPK (EC50 = 11.7 µM). It is thought to activate AMPK by inhibiting mitochondrial complex I, producing an increase in AMP levels. AMPK activator stimulates glucose uptake in L6 myocytes and promotes phosphorylation of acetyl-CoA carboxylase, a known target of AMPK. AMPK activator also decreases blood glucose concentrations in female Zucker diabetic rats, demonstrating its utility in whole animals. At 50 µM, it inhibits the growth of multiple myeloma cells. AMPK activator induces phosphorylation of raptor in PC3 prostate cancer cells, down-regulating mTORC1 signaling and reducing survivin expression. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic acid, D942 |
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| Gene, Accession, CAS # | CAS: 849727-81-7 |
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| Catalog # | LS-H6529 |
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| Order / More Info | AMPK activator from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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