| 产品详情 |
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| Product Name | KT 5823 |
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| Description | Purity >95%. The activity of cGMP-dependent protein kinase (PKG) is controlled by factors that elevate cellular cGMP, like nitric oxide (NO), and by those that reduce cGMP levels, like certain phosphodiesterases. KT 5823 is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50 = 234 nM). KT 5823 is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells. KT 5823 is a weak inhibitor of PKC (Ki = 4 µM) and PKA (Ki >10 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9S,12R-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester |
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| Gene, Accession, CAS # | CAS: 126643-37-6 |
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| Catalog # | LS-H8366 |
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| Price | |
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| Order / More Info | KT 5823 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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