| 产品详情 |
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| Product Name | KT195 |
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| Description | Purity >98%. The serine hydrolase known as Alpha/Beta-hydrolase domain-containing protein 6 (ABHD6) hydrolyzes 2-arachidonoyl glycerol (2-AG) to regulate its availability at cannabinoid receptors. KT195 is a selective inhibitor of ABHD6 (IC50 = 10 nM) with negligible activity against other serine hydrolases such as DAGLBeta. While it can be used as a probe to study ABHD6, it also has use as a negative control for studies of DAGLBeta. By inactivating ABHD6, KT195 has been shown to induce a significant accumulation of 2-AG in Neuro2a cells. KT195 is also reported to reduce IL-1Beta secretion from lipopolysaccharide-treated macrophages. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [4-(4'-methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone, ML-295 |
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| Gene, Accession, CAS # | CAS: 1402612-58-1 |
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| Catalog # | LS-H8372 |
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| Price | |
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| Order / More Info | KT195 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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