| 产品详情 |
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| Product Name | D609 (potassium salt) |
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| Description | Purity >90%. Phosphatidylcholine-specific phospholipase C (PC-PLC) cleaves PC to generate diacylglycerol and phosphocholine. D609 is a xanthate that acts as a competitive inhibitor of PC-PLC (Ki = 6.4 µM). It does not affect bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 also reduces sphingomyelin synthase activity, both in membrane preparations (IC50 = 100 µg/ml) and in cells. Like other xanthates, D609 has antioxidant, antiviral, and anti-tumor activities. In addition, it has anti-inflammatory actions, blocking the induction of nitric oxide synthase by LPS in phagocytes (IC50 = 20 µg/ml) and the expression of vascular cell adhesion molecule 1 by IL-1Beta in endothelial cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | O-(octahydro-4,7-methano-1H-inden-5-yl) ester, carbonodithioic acid, monopotassium salt, Tricyclodecan-9-yl xanthogenate |
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| Gene, Accession, CAS # | CAS: 83373-60-8 |
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| Catalog # | LS-H7339 |
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| Price | |
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| Order / More Info | D609 (potassium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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