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| Product Name | Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 34.7kDa. Full Length of Mature Protein: 23-190aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NR sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous syst and male reproductive syst. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Beta-trace protein; Cerebrin-28Glutathione-independent PGD synthaseLipocalin-type prostaglandin-D synthaseProstaglandin-D2 synthase; PGD2 synthase; PGDS; PGDS2 |
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| Gene, Accession, CAS # | PTGDS, UniProt: P41222 |
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| Catalog # | RPC20067 |
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| Order / More Info | Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS) from BIOMATIK |
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| Product Specific References | n/a |
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