| 产品详情 |
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| Antigenic Specificity | Apoa5(ab) (aa 20-363) |
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| Clone | 1G5G9(c) |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower , concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins. |
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| Immunogen | Purified recombinant fragment of human APOA5 (AA 20-363) expressed in E. coli. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN969468 |
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| Price | |
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| Order / More Info | Apoa5(ab) (aa 20-363) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 11588264, 12709436 |
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