| 产品详情 |
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| Antigenic Specificity | HDAC4 |
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| Clone | 14H4L10 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HDAC4 Antibody (14H4L10), ABfinity™ Rabbit Monoclonal. Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly- |
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| Immunogen | n/a |
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| Other Names | Histone deacetylase 4 |
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| Gene, Accession # | Entrez: 363287, 9759; Uniprot: P56524, Q99P99 |
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| Catalog # | 702358 |
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| Price | |
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| Order / More Info | HDAC4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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