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| Product Name | Recombinant Mouse Tumor necrosis factor protein (Tnf) (Active) |
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| Description | Purity > 98% as determined by SDS-PAGE and HPLC. MW: 17.4kDa. Partial: 80-235aa. tag-Free. Mus musculus (Mouse). Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.; The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells. {ECO:0000250}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cachectin, Tumor necrosis factor ligand superfamily member 2, TNF-a,, NTF |
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| Gene, Accession, CAS # | Tnf,Tnfa,Tnfsf2, UniProt: P06804 |
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| Catalog # | RPC26731 |
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| Order / More Info | Recombinant Mouse Tumor necrosis factor protein (Tnf) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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