| 产品详情 |
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| Antigenic Specificity | TNFR1 |
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| Clone | 12HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:20, Western Blot: 2-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNFR1 Antibody (12HCLC), ABfinity™ Rabbit Oligoclonal. TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transdu |
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| Immunogen | n/a |
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| Other Names | CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60, TNF-R1, TNF-RI, TNFR-I, tumor necrosis factor binding protein 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor type 1, tumor necrosis factor-alpha receptor |
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| Gene, Accession # | Entrez: 7132; Uniprot: P19438 |
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| Catalog # | 710368 |
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| Price | |
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| Order / More Info | TNFR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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