产品详情 |
Edit |   |
Antigenic Specificity | CCR3 |
Clone | 23H17L1 |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR3 Antibody (23H17L1), ABfinity™ Rabbit Monoclonal. CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. |
Immunogen | n/a |
Other Names | CMKBR3 |
Gene, Accession # | Entrez: 1232; Uniprot: P51677 |
Catalog # | 702231 |
Price | |
Order / More Info | CCR3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|