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| Product Name | NCC4 - Control Lysate |
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| Description | NCC-4 (also known as HCC-4) is a CC chemokine. It is a 97 amino acid protein. It exhibits less than 30% sequence identity to other CC chemokines. NCC-4 chemoattracts human monocytes and THP-1 cells. However it does not chemoattract resting lymphocytes or neutrophils. It has been found to supress proliferation of myeloid progenitor cells and induces calcium flux in THP-1 cells. This calcium flux can be desensitized by exposure to RANTES which suggests that NCC-4 and RANTES share the same receptor |
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| Size | 0.02 mg |
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| Concentration | n/a |
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| Applications | Activity Assay |
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| Other Names | n/a |
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| Gene, Accession, CAS # | [NCC4] |
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| Catalog # | MBS570453 |
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| Order / More Info | NCC4 - Control Lysate from MYBIOSOURCE INC. |
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| Product Specific References | 1. Verstraeten, A.A. et al. Tenascin expression in basal cell carcinoma. Br. J. Dermatol. 1992, 127, 571-574. 2. Le Poole, I.C., et al. Tenascin is overexpressed in vitiligo lesional skin and inhibits melanocyte adhesion. Br. J. Dermatol. 1997, 137, 171-178. 3. Rulo, H.F., et al. Normal human skin demonstrates marked site-variation of tenascin expression, not correlated to epidermal proliferation (Ki-67 binding). J. Dermatol. Sci. 1993, 5, 54-57 |
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