| 产品详情 |
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| Antigenic Specificity | Leucine-Rich Repeat Kinase 2 (LRRK2) (N-Term), (aa 1-500) |
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| Clone | S138-6 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | biotin conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Immunofluorescence (IF),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features.Cellular Localization: Cytoplasm, Membrane, Mitochondrion, Perikaryon, Golgi apparatus, Cell projection | axon, Endoplasmic reticulum, Cytoplasmic vesicle, Endosome, Lysosome |
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| Immunogen | Fusion protein, amino acids 1-500 (N-terminus) of human LRRK2. 83% identical in mouse and rat. No significant identity with LRRK1. |
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| Other Names | LRRK2|AURA17|DARDARIN|PARK8|RIPK7|ROCO2|4921513O20Rik|9330188B09Rik|AW561911|D630001M17Rik|Gm927|cI-46 |
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| Gene, Accession # | Gene ID: 120892,66725,300160 |
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| Catalog # | ABIN1741046 |
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| Price | |
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| Order / More Info | Leucine-Rich Repeat Kinase 2 (LRRK2) (N-Term), (aa 1-500) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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