| 产品详情 |
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| Antigenic Specificity | C11orf30 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | C11orf30 Polyclonal Antibody. EMSY interacts with BRCA2 and plays a role in chromatin remodeling. This interaction has been confirmed in HeLa cells. Overexpression of EMSY strongly correlates with amplification in sporadic breast cancer and higher grade ovarian cancer. The EMSY gene is amplified in 18% of breast cancer cell lines. EMSY amplification is highly correlated with DNA amplification in both cell lines and primary tumors. This amplification is a general sign of poor prognosis and shortened disease-free survival time. EMSY from a wide variety of species has a conserved 80 amino acid sequence at the N-terminus. In irradiated MEFs (mouse embryonic fibroblasts), EMSY was found to migrate to damaged DNA. |
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| Immunogen | n/a |
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| Other Names | C11orf30; Chromosome 11 open reading frame 30; EMSY protein; FLJ90741; GL002; Protein EMSY; |
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| Gene, Accession # | Entrez: 56946; Uniprot: Q7Z589 |
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| Catalog # | PA5-76850 |
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| Price | |
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| Order / More Info | C11orf30 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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