| 产品详情 |
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| Product Name | Borrelidin |
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| Description | Purity >98% by HPLC. Macrolide antibiotic. Bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Cyclin-dependent kinase (CDK) inhibitor. Antiviral. Potent antimalarial agent (IC50 = 0.97 nM). Inhibitor of potato scab disease. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | C2989, Treponemycin, U 78548 |
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| Gene, Accession, CAS # | CAS: 7184-60-3 |
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| Catalog # | LS-H734 |
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| Price | |
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| Order / More Info | Borrelidin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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