| 产品详情 |
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| Product Name | Ch 55 |
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| Description | Purity >98%. Ch 55 is a synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Ki s in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM). Ch 55 has been shown to inhibit squamous cell differentiation of rabbit tracheal epithelial cells by inhibiting type I transglutaminase activity (EC50 = 0.02 nM) and increasing cholesterol sulfate levels (EC50 = 0.03 nM). In contrast, it has also been shown to induce differentiation of embryonic carcinoma F9 cells and melanoma S91 cells (EC50 s = 0.26 and 0.5 nM, respectively), as well as inhibit the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(1E)-3-[3,5-bis (1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]-benzoic acid |
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| Gene, Accession, CAS # | CAS: 110368-33-7 |
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| Catalog # | LS-H7098 |
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| Price | |
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| Order / More Info | Ch 55 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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