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| Antigenic Specificity | Kruppel-Like Factor 4 (Gut) (KLF4) |
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| Clone | 3B3-B11-E6 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG2b |
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| Format | unconjugated |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells,and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. Subunit structure: Interacts with POU5F1/OCT4 and SOX2 by similarity. Interacts with MUC1 (via the C-terminal domain). Interacts with MEIS2 isoform 4 and PBX1 isoform PBX1a. Subcellular location: Nucleus. Sequence similarities: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
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| Immunogen | Purified recombinant mouse KLF4 protein fragments expressed in E.coli. |
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| Other Names | KLF4|EZF|GKLF|biklf|biklf-A|Gklf|Zie |
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| Gene, Accession # | Gene ID: 16600 |
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| Catalog # | ABIN2169543 |
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| Price | |
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| Order / More Info | Kruppel-Like Factor 4 (Gut) (KLF4) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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