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| Product Name | Interleukin 1 delta (FIL1d) (AA 1-155) protein |
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| Description | Human Interleukin-36 Receptor Antagonist (IL-36RN) is a secreted protein which belongs to the Interleukin 1 cytokine family (IL-1 family). IL-36RN is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. IL-36RN is also detected in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin. IL-36RN is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to Interleukin 1 family member 9 (IL1F9). Dysregulated expression of novel agonistic and antagonistic IL-1 family member ligands can promote cutaneous inflammation, revealing potential novel targets for the treatment of inflammatory skin disorders. Human and mouse IL-36RN share 90% sequence identity.Alternative Names: Interleukin-36 Receptor Antagonist Protein, FIL1 Delta, IL-1-Related Protein 3, IL-1RP3, Interleukin-1 HY1, IL-1HY1, Interleukin-1 Delta, IL-1 Delta, Interleukin-1 Family Member 5, IL-1F5, Interleukin-1 Receptor Antagonist Homolog 1, IL-1ra Homolog 1, Int |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AI413231|Fil1delta|IL36RN|Il-1h3|Il1hy1|FIL1|FIL1(DELTA)|FIL1D|IL1F5|IL1HY1|IL1L1|IL1RP3|IL36RA|PSORP|Il1f5 |
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| Gene, Accession, CAS # | Gene ID: 26525 |
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| Catalog # | ABIN1096952 |
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| Order / More Info | Interleukin 1 delta (FIL1d) (AA 1-155) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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