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| Antigenic Specificity | Phospho-p70 S6 Kinase (Thr421, Ser424) |
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| Clone | B12HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Western Blot: 1:500-1:5000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-p70 S6 Kinase (Thr421, Ser424) Antibody (B12HCLC), ABfinity™ Rabbit Oligoclonal. The p70 S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70 kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70 S6 kinase is predominantly localized in the cytoplasm, and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response, and tissue repair. p70 S6 kinase acts downstream of phosphoinositide (PI) 3-kinase, and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70 S6 kinase leads to an increase in protein synthesis and cell proliferation. Am |
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| Immunogen | n/a |
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| Other Names | 70 kDa ribosomal protein S6 kinase 1, P70S6K1, S6K-beta-1, p70 S6 kinase alpha, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, p70 S6K-alpha, p70 S6KA, p70 ribosomal S6 kinase alpha, p70-S6K 1, ribosomal protein S6 kinase I, ribosomal protein S6 kinase beta-1, serine/threonine kinase 14 alpha, serine/threonine-protein kinase 14A |
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| Gene, Accession # | Entrez: 6198; Uniprot: P23443 |
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| Catalog # | 710108 |
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| Price | |
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| Order / More Info | Phospho-p70 S6 Kinase (Thr421, Ser424) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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