产品详情 |
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Antigenic Specificity | Phospho-Rb (Thr821) |
Clone | 16H2L1 |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Western Blot: 2-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-Rb (Thr821) Antibody (16H2L1), ABfinity™ Rabbit Monoclonal. Rb, also known as Retinoblastoma, is a tumor suppressor protein that keeps uncontrolled growth and division in check. Rb belongs to the Pocket Protein family whose members have a pocket for binding proteins. It is nuclear protein which is widely expressed in retinal cells. It is inactivated by phosphorylation and activated by dephosphorylation. Phosphorylation of serine 249 and threonine 252 is catalyzed by Cyclin D-cdk4. In humans, the protein is encoded by the RB1 gene located on the q arm of chromosome 13. |
Immunogen | n/a |
Other Names | Retinoblastoma-associated protein, PP110, P105-RB, RB, RB1, OSRC, p105-Rb, pRb, pp110 |
Gene, Accession # | Entrez: 5925; Uniprot: P06400 |
Catalog # | 701290 |
Price | |
Order / More Info | Phospho-Rb (Thr821) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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