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| Product Name | Recombinant Human Frataxin, mitochondrial (FXN) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 43.1kDa. Full Length: 1-210aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Frataxin; mitochondrial |
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| Gene, Accession, CAS # | FXN, UniProt: Q16595 |
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| Catalog # | RPC22971 |
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| Price | |
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| Order / More Info | Recombinant Human Frataxin, mitochondrial (FXN) from BIOMATIK |
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| Product Specific References | n/a |
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