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| Product Name | Dio3, Recombinant, Rat, aa37-278, His-Tag (Type III Iodothyronine Deiodinase) |
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| Description | Purity ~90% (SDS-PAGE). Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development. Source: Recombinant protein corresponding to aa37-278 from rat Dio3, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~31.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5DIIIDIOIIIType 3, DIType-III 5'-deiodinase |
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| Gene, Accession, CAS # | SwissProt: P49897 |
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| Catalog # | 373057 |
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| Order / More Info | Dio3, Recombinant, Rat, aa37-278, His-Tag (Type III Iodothyronine Deiodinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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