| 产品详情 |
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| Product Name | ALK-IN-1 |
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| Description | Purity >98%. ALK-IN-1 is an analog of AP26113, a phosphine oxide-containing ALK inhibitor. ALK-IN-1 potently inhibits ALK (IC50 = 0.07 nM) over IGF-1R and InsR (IC50 s = 3.2 and 100 nM, respectively). It drives cell death in (ALK+) Karpas-299 lymphoma cells with an IC50 value of 41.5 nM, while killing (ALK-) U937 cells with an IC50 value of 1,718 nM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-chloro-N2 -[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4 -[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine |
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| Gene, Accession, CAS # | CAS: 1197958-12-5 |
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| Catalog # | LS-H6477 |
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| Order / More Info | ALK-IN-1 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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