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| Product Name | Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (Active) protein |
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| Description | BCA-1 is a CXC chemokine that is highly expressed in the secondary lymphoid organs, such as follicles of the spleen, lymph nodes, and Peyer's patches. CXCL13 promotes the migration of B lymphocytes (compared to T cells and macrophages), by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR1). BCA1 therefore function in the homing of B lymphocytes to follicles. Human BCA-1 shares a 64 % amino acid sequence similarity with the mouse protein and 23 - 34 % amino acid sequence identity with other known CXC chemokines. Recombinant or chemically synthesized BCA1 is a potent chemoattractant for B lymphocytes but not T lymphocytes, monocytes or neutrophils. BLR1, a G protein-coupled receptor originally isolated from Burkitt's lymphoma cells, has now been shown to be the specific receptor for BCA1. Among cells of the hematopoietic lineages, the expression of BLR-1, now designated CXCR-5, is restricted to B lymphocytes and a subpopulation of T helper memory cells Synonyms: C-X-C motif chemokine 13, Small-inducible cytokine B13, B lymphocyte chemoattractant, CXC chemokine BLC, CXCL13, BCA1, BCA-1, CXCL-13, B cell Attracting Chemokine-1, BLC, ANGIE, BLR1L, SCYB13, ANGIE2 |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4631412M08Rik|ANGIE2|Angie|BCA-1|BLC|BLR1L|Scyb13|ANGIE|BCA1|SCYB13 |
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| Gene, Accession, CAS # | Gene ID: 10563 |
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| Catalog # | ABIN803720 |
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| Order / More Info | Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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