| 产品详情 |
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| Product Name | CID755673 |
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| Description | Purity >98%. Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CID755673 is a small molecule inhibitor of PKD (IC50 s = 182, 280, 227 nM for PKD1, 2, and 3, respectively) that exhibits higher selectivity for PKD over Akt, polo-like kinase 1, CDK activating kinase, CAMKII and three different PKC isoforms (IC50 s range from 15 to > 50 µM). At 25 µM, CID755673 has been shown to inhibit prostate cancer cell proliferation, cell migration, and invasion. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,3,4,5-tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one |
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| Gene, Accession, CAS # | CAS: 521937-07-5 |
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| Catalog # | LS-H7139 |
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| Price | |
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| Order / More Info | CID755673 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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