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Antigenic Specificity | CD8a Molecule (CD8A) |
Clone | RAVB3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA,Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck. |
Immunogen | Purified recombinant fragment of human CD8 expressed in E. coli. |
Other Names | cd8|LOC100136450|BB154331|Ly-2|Ly-35|Ly-B|Lyt-2|zgc:136643|CD8|Leu2|MAL|p32|RHACD8-4 |
Gene, Accession # | Gene ID: 925 |
Catalog # | ABIN969474 |
Price | |
Order / More Info | CD8a Molecule (CD8A) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 3262426 |