| 产品详情 |
| Edit |   |
|---|
| Product Name | (S)-Ibuprofen |
|---|
| Description | Purity >98%. Ibuprofen is a non-steroidal anti-inflammatory drug with diverse biochemical actions, most notably inhibiting COX-1 and COX-2 (IC50 s = 2.6 and 1.53, µM, respectively). It is commonly synthesized as a racemic mixture of (S)- and (R)-isomers. (S)-Ibuprofen is an enantiomer that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form. (S)-Ibuprofen also inhibits activation of NF-KappaB more effectively than (R)-ibuprofen (IC50 s = 62 and 122 µM, respectively). However, the enantiomers are equipotent in blocking superoxide formation, Beta-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 values range from 0.14 to 0.58 µM). A majority of (R)-ibuprofen can be inverted to (S)-ibuprofen in humans after oral administration. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (aS)-a-methyl-4-(2-methylpropyl)-benzeneacetic acid, (+)-Ibuprofen, Dexibuprofen |
|---|
| Gene, Accession, CAS # | CAS: 51146-56-6 |
|---|
| Catalog # | LS-H5680 |
|---|
| Price | |
|---|
| Order / More Info | (S)-Ibuprofen from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|