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| Product Name | Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (Active) protein |
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| Description | Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and to chemoattract and activate neutrophils. Although CTAP-III, beta-TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity. Synonym: NAP-2 /CXCL7, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2400003M24Rik|AI854500|CTAP3|CTAPIII|Cxcl7|LA-PF4|LDGF|MDGF|NAP-2|NAP-2-L1|Scyb7|TGB|TGB1|THBGB1|b-TG1|beta-TG|B-TG1|Beta-TG|CTAP-III|CXCL7|PBP|SCYB7|TC1|TC2|THBGB|Nap-2|CTAPIII/NAP-2 |
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| Gene, Accession, CAS # | Gene ID: 5473 |
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| Catalog # | ABIN988173 |
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| Order / More Info | Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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