| 产品详情 |
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| Product Name | Biochanin A |
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| Description | Purity >98%. Biochanin A is a natural isoflavone with diverse biological actions, most notably as a phytoestrogen. It can affect hormone levels by inhibiting 5Alpha-reductase and 17Beta-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity. Also known as 4'-methyl genistein, biochanin A can be metabolized in vivo to genistein , another phytoestrogen with diverse effects. Biochanin A also intersects with signaling through peroxisome proliferator-activated receptors (PPARs), as it activates PPARGamma (IC50 = 19 µM) and has also been shown to activate a PPARAlpha promoter. Moreover, it increases the expression of the PPARGamma coactivator PGC-1Alpha, promoting mitochondrial biogenesis. Biochanin A also inhibits fatty acid amide hydrolase (IC50 = 2.4 µM) and acts as an agonist of the aryl hydrocarbon receptor (EC50 = 0.25 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 4'-methyl Genistein, 5,7-dihydroxy-4'-Methoxyisoflavone, NSC 123538 |
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| Gene, Accession, CAS # | CAS: 491-80-5 |
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| Catalog # | LS-H6817 |
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| Order / More Info | Biochanin A from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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