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| Product Name | MAT1A, 1-395aa, Human, His tag, E Coli |
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| Description | MW: 45.6 kDa (414aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFkappaB and TNFalpha cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [S-adenosylmethionine synthetase; MAT; MATA1; SAMS; SAMS1; methionine adenosyltransferase I alpha; S-adenosylmethionine synthetase; MAT1A,] |
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| Gene, Accession, CAS # | MAT1A, Gene ID: 4143, Accession: NP_000420 |
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| Catalog # | MBS203716 |
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| Order / More Info | MAT1A, 1-395aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Ding W., et al. (2009) Hepatology. 49 (4):1277-86. ; Tomasi ML., et al. (2009) Gastroenterology. 136 (3):1025-36.; |
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