| 产品详情 |
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| Product Name | (S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide |
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| Description | Purity >98%. N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Linoleoyl ethanolamide (LOEA) has potential signaling roles in aging and neurological functioning. LOEA has a weak affinity for cannabinoid (CB) receptors (Ki = 10 and 25 µM for CB1 and CB2, respectively). It also inhibits fatty acid amide hydrolase (FAAH; Ki = 9 µM) and is hydrolyzed by FAAH, and inhibits voltage-gated K+ channels. (S)-(-)-Linoleyl-1'-hydroxy-2'-propylamide is a homolog of LOEA, characterized by the addition of an (S)-Alpha-methyl group at the methylene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide to produce S-1 methanandamide results in a diminished affinity for the CB receptor but greatly improved metabolic stability to aminopeptidase hydrolysis. The physiological actions of this compound have not been evaluated. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-((S)-1-hydroxypropan-2-yl)octadeca-9Z,12Z-dienamide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H5660 |
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| Order / More Info | (S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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